After a lumbar puncture, which finding would require immediate MD contact due to potential complication?

• A. Fever
• B. Changes in LOC
• C. Decreased strength
• D. Leakage of CSF

Answer: (D)

Leakage of CSF at the puncture site is a direct post-procedure complication that signals ongoing CSF loss. When CSF continues to escape, intracranial pressure can drop (intracranial hypotension), leading to severe headaches and, in some cases, serious outcomes like infection (meningitis) or subdural problems. Because this situation can worsen quickly, it requires immediate assessment and intervention by a clinician. The other findings—fever, changes in consciousness, or new weakness—are concerning and warrant prompt evaluation as well, but they do not indicate a CSF leak at the puncture site itself, which is the clearest red flag that needs urgent medical attention.