In Meniere's disease, why are antihistamines and diuretics prescribed?

• A. To reduce fluid in the ear and relieve vertigo
• B. To treat infection
• C. To improve bone conduction
• D. To prevent hearing loss

Answer: (A)

Managing Menière's disease aims to reduce the abnormal fluid buildup in the inner ear (endolymphatic hydrops) to lessen vertigo. Diuretics help by lowering overall fluid volume, which leads to less endolymphatic pressure in the inner ear and, as a result, fewer vertigo episodes. Antihistamines provide relief by dampening vestibular (balance) signals and offering antiemetic effects, helping with the dizziness and nausea that accompany attacks. This combo targets the fluid imbalance and its main symptom—vertigo—rather than treating infection, changing bone conduction, or preventing hearing loss, making it the best approach among the options.