People who suffer from migraines are at increased risk for which conditions?

• A. Stroke and epilepsy
• B. Hypertension
• C. Diabetes
• D. Asthma

Answer: (D)

Migraines often occur alongside other inflammatory or atopic conditions, reflecting overlapping pathways in the body's response to triggers. In migraines, activation of the trigeminovascular system releases inflammatory peptides like CGRP, leading to vascular and neural inflammation. Asthma involves airway inflammation with similar inflammatory mediators and a tendency toward atopy. This shared inflammatory environment and common triggers (such as allergens, stress, weather changes) help explain why asthma is a frequently observed comorbidity in people with migraines. While there may be associations with stroke risk (especially with aura) or other conditions in some studies, the link to asthma is the most consistently recognized in this context.